An antibacterial sheath is suitable for detachably covering an object to be covered, and includes a sleeve unit that defines a sleeve space for accommodating the object to be covered, and the sleeve unit includes a base body A layer and two antibacterial layers which are respectively covered on the inner and outer sides of the base layer and have antibacterial functions. With the inner and outer covering designs of the antibacterial layers, comprehensive antibacterial protection can be achieved, the antibacterial ability of the antibacterial sheath is enhanced, and the use is more hygienic and safer.一種抗菌護套,適用於可脫離地包覆一待套物,並包含一套體單元,該套體單元界定出一可供容納該待套物的套置空間,該套體單元包括一基體層,及二分別被覆於該基體層之內、外兩相反側面且具有抗菌功能的抗菌層。藉由該等抗菌層之內外被覆設計,可全面抗菌防護,增強該抗菌護套的抗菌能力,使用上也更加衛生安全有保障。