THE BRIGHAM AND WOMEN'S HOSPITAL; INC.;THE BRIGHAM AND WOMENS HOSPITAL
发明人:
BLUMBERG, RICHARD S.,HUANG, YU-HWA,UTKU, NALAN
申请号:
EP12854214
公开号:
EP2785743A4
申请日:
2012.11.30
申请国别(地区):
EP
年份:
2015
代理人:
摘要:
Provided herein are recombinant monoclonal antibodies and antigen-binding portions thereof useful in inhibiting CEACAM1 in tumor cells, and methods of their use in anti-tumor proliferation and invasiveness therapies, such as the treatment of cancer, particularly pancreatic cancer.