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TASK-LESS OPTICAL MAPPING OF BRAIN FUNCTION USING RESTING STATE FUNCTIONAL CONNECTIVITY
专利权人:
发明人:
Joseph P. Culver,Brian R. White,Bradley L. Schlaggar,Abraham Z. Snyder,Marcus E. Raichle,Michael D. Fox,Justin L. Vincent
申请号:
US15281765
公开号:
US20170014066A1
申请日:
2016.09.30
申请国别(地区):
US
年份:
2017
代理人:
摘要:
A method for utilizing an optical system for taskless mapping of brain function includes determining a time series of dynamic light measurements for a plurality of spatially distributed source-detector pairs, receiving the dynamic light measurements over a period of time using the source-detector pairs without dependence on either a task or a change in physiological condition, generating a plurality of temporal correlations between regions of a brain for the light measurements based on the time series of the spatially distributed source-detector pairs and the received dynamic light measurements, producing at least one map of a respective strength of each of a plurality of temporal correlations, producing overlapping source-detector pairs measurements using diffuse optical tomography (DOT) geometries, reconstructing data representative of the dynamic light measurements into an image space using at least one DOT algorithm, and co-registering DOT voxel images obtained by the reconstruction to anatomical information.
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