Compositions and methods directed to treating liver fibrosis

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专利权人:

Alnylam Pharmaceuticals; Inc.

发明人:

Hinkle, Greg,Kotelianski, Victor,Bettencourt, Brian,Sehgal, Alfica,Novobrantseva, Tatiana

申请号：

AU2011261434

公开号：

AU2011261434B2

申请日:

2011.06.02

申请国别(地区):

AU

年份:

2015

代理人:

摘要：

The invention relates to double-stranded ribonucleic acid (dsRNA) compositions targeting the COL1A1, TGF-β, and SMAD2/3 genes, and methods of using such dsRNA compositions to inhibit expression of COL1A1, TGF-β, and SMAD2/3.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/