NOUVEAUX COMPOSES CAPABLES D'AVOIR UN EFFET ANTAGONISTE SUR LES LESIONS DES CELLULES BETA INDUITES PAR LE POLYPEPTIDE D'ACIDES AMINES (IAPP) ET L'INTOLERANCE AU GLUCOSE

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专利权人:

NEURIMMUNE HOLDING AG;UNIVERSITY OF ZURICH

发明人:

GRIMM, JAN,HEITZ, FABRICE,WIRTH, FABIAN,WELT, TOBIAS

申请号：

CA2942120

公开号：

CA2942120A1

申请日:

2015.03.12

申请国别(地区):

CA

年份:

2015

代理人:

摘要：

Described are molecules specifically binding to human islet amyloid polypeptide (hIAPP) also known as amylin, particularly human-derived antibodies as well as fragments, derivatives and variants thereof for antagonizing islet amyloid polypeptide (IAPP) induced ß-cell damage and impaired glucose tolerance which are symptoms typically associated with diabetes mellitus type 2 (T2D).

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中国工程科技知识中心

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http://www.ckcest.cn/home/