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Salts, co-crystals, and polymorphs of an anxiolytic compound
专利权人:
Bionomics Limited;Ironwood Pharmaceuticals, Inc.
发明人:
Bernard Luke Flynn,Dharam Paul,Andrew John Harvey,Vasu V. Sethuraman,Raymond E. Forslund,Song Xue,Rob Livingston,Ahmad Hashash
申请号:
US14776643
公开号:
US09745296B2
申请日:
2014.03.14
申请国别(地区):
US
年份:
2017
代理人:
摘要:
The present invention provides amorphous arid crystalline forms of 1-ethyl-6-(indan-2-ylamino)-3-(morpholine-4-carbonyl)-1,8-naphthyridin-4-one (compound 1), and salts, co-crystals, and pharmaceutical compositions thereof. The invention also provides methods of treating and/or preventing a disease, such as a central nervous system disease (e.g., an anxiety disorder), using the amorphous and crystalline forms, and salts, co-crystals, and pharmaceutical compositions thereof.
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