A composition comprising a non-covalent association complex of: (a) a positively charged polymeric backbone having covalently linked thereto a plurality of positively charged amino acid sequences selected from - (gly) n1 - (arg) n2, in that n1 is an integer from 0 to 20 and n2 is an odd integer from 5 to 25； (gly) p-RGRDDRRQRRR- (gly) q； (gly) p- YGRKKRRQRRR- (gly) q, in which the subscripts p and q are each, independently, an integer from 0 to 20； or a positively charged HIV TAT peptide domain； and (b) at least two members selected from the group consisting of: i) a first negatively charged main chain having a plurality of attached imaging moieties； ii) a second negatively charged main chain having a plurality of linked address agents； and iii) a third negatively charged main chain having a plurality of bound biological agents； wherein each of said biological agents is a therapeutic or cosmeceutical agent selected from the group consisting of botulinum toxin, EGF, TGF-β1, insulin, VEGF, a VEGF blocker and antibodies against VEGF； wherein said non-covalent association complex carries a positive net charge and at least one of said two members of (b) is selected from group i) or group iii).Una composición que comprende un complejo de asociación no covalente de: (a) una cadena principal polimérica cargada positivamente que tiene unida covalentemente a la misma una pluralidad de secuencias de aminoácidos cargadas positivamente seleccionadas de -(gly)n1 -(arg)n2, en la que n1 es un número entero de 0 a 20 y n2 es un número entero impar de 5 a 25； (gly)p-RGRDDRRQRRR-(gly)q； (gly)p- YGRKKRRQRRR-(gly)q, en la que los subíndices p y q son cada uno, independientemente, un número entero de 0 a 20； o un dominio peptídico TAT de VIH cargado positivamente； y (b) al menos dos miembros seleccionados del grupo que consiste en: i) una primera cadena principal cargada negativamente que tiene una pluralidad de restos de formación de imágenes unidos； ii) una segunda cadena principal car
