Cristianne Johanna Ferdinand RIJCKEN,Josephus Johannes Maria HOLTHUIS
申请号：
US14775642
公开号：
US20160030348A1
申请日:
2014.03.10
申请国别(地区):
US
年份:
2016
代理人:
摘要：
The present invention is directed to vaccination composition comprising a particle comprising a polymer matrix incorporating an adjuvant and/or an antigen, to method of making them and use. Particularly, the present invention results in adjuvants and/or antigens, covalently entrapped in or coupled to polymer carriers or polymeric devices, such as micelles, nanoparticles, microspheres and other types of polymer devices for controlled release； the adjuvant and/or antigen are covalently bonded in or to the polymer carriers or polymeric devices.
