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(+)-alpha-dihydrotetrabenazine for use in the treatment a movement disorder
专利权人:
Adeptio Pharmaceuticals Limited
发明人:
Duffield, Andrew John,Pandya, Anant
申请号:
AU2018242134
公开号:
AU2018242134A1
申请日:
2018.03.29
申请国别(地区):
AU
年份:
2019
代理人:
摘要:
The invention relates to the use of low doses of (+)-α-dihydrotetrabenazine for the treatment of movement disorders, such as Tourette's syndrome. The invention provides (+)-α-Dihydrotetrabenazine or pharmaceutically acceptable salt thereof for use in a method of treating a movement disorder in a subject in need thereof, which method comprises steps of administering to the subject an initial daily dosage of (+)-α-dihydrotetrabenazine or pharmaceutically acceptable salt thereof, wherein the initial daily dosage is an amount of (+)-α-dihydrotetrabenazine or pharmaceutically acceptable salt thereof corresponding to from 0.5 mg to 5 mg of (+)-α-dihydrotetrabenazine free base, carrying out a clinical evaluation of the subject, either maintaining the initial daily dosage, increasing or reducing the dosage, or discontinuing the treatment. The method aims at reaching an optimum daily dosage.
来源网站:
中国工程科技知识中心
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http://www.ckcest.cn/home/

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