Kristin Wilson Cerione;Richard A. Cerione;Jianbin Wang;Jon W. Erickson
发明人:
Richard A. Cerione,Jon W. Erickson,Kristin Wilson Cerione,Jianbin Wang
申请号:
US13259533
公开号:
US20120220610A1
申请日:
2010.03.25
申请国别(地区):
US
年份:
2012
代理人:
摘要:
The present invention relates to a method of reducing the production of glutamate from glutamine by glutaminase C in a cell or tissue. The method involves inhibiting glutaminase C activity in the cell or tissue under conditions effective to reduce production of glutamate from glutamine. Compounds for carrying out this method are also disclosed.