This invention is a benzothiophene estrogen receptor modulator or its pharmaceutically acceptable salt or a pharmaceutically acceptable composition thereof to treat an estrogen-related medical disorder.本發明為一種治療雌激素相關醫學病症之苯并噻吩雌激素受體調節劑或其醫藥學上可接受之鹽或其醫藥學上可接受之組合物。