Kura Oncology, Inc.;The Regents of The University of Michigan
发明人:
GREMBECKA, Jolanta,CIERPICKI, Tomasz,BORKIN, Dmitry,POLLOCK, Jonathan,LI, Liansheng,WU, Tao,FENG, Jun,REN, Pingda,LIU, Yi
申请号：
EP20160804583
公开号：
EP3302057(A1)
申请日:
2016.06.03
申请国别(地区):
欧洲专利局
年份:
2018
代理人:
摘要：
The present disclosure provides compositions and methods of use to inhibit the interaction of menin with MLL1, MLL2 and MLL-fusion oncoproteins. The compositions and methods of use are useful for the treatment of leukemia, solid cancers, diabetes and other diseases dependent on activity of MLL1, MLL2, MLL fusion proteins, and/or menin.
