Disclosed is The use of an effective amount of 17alpha-acetoxy-11beta-[4-N, N-dimethylamino-phenyl)-19-norpregna- 4, 9-diene-3, 20-dione (ulipristal acetate) or any metabolite thereof for the manufacture of a medicament for reducing or stopping bleeding in a patient afflicted with uterine fibroids; preventing or treating anaemia in a patient afflicted with uterine fibroids or treating metastatic leiomyoma. The ulipristal acetate metabolite is selected from the group consisting of CDB-3877, CDB-3963, CDB-3236, and CDB-4183.