The invention relates to the field of medicine and pharmacy, in particular to the creation of a pharmaceutical composition in the form of a suspension for the prevention and treatment of disorders of the physiological and reparative regeneration of tissues of the musculoskeletal system - bone tissue and articular cartilage, in particular for the treatment of osteoporosis. The pharmaceutical composition for the prevention and treatment of disorders of the physiological and reparative regeneration of tissues of the musculoskeletal system - bone tissue and articular cartilage, includes dimephosphon (dimethyloxobutylphosphonyl dimethylate), calcium carbonate in the form of the substance "Calcium carbonate and magnesium micellate", sodium polysaccharide-hyalurium sodium salt in the following ratio of components, wt.%: The pharmaceutical composition as an auxiliary substance contains alcohol, nipagin, fructose. Studies have shown that the proposed pharmaceutical compositions have a pronounced specific pharmacological effect, exhibiting a reparative-regenerative effect in relation to the bone tissue of animals, and do not have a pronounced general toxic effect at various doses and routes of entry into the body of experimental animals. Compositions do not have an irritating effect, no sensitizing effect was found. The proposed pharmaceutical compositions are effective and safe and can be used for the prevention and treatment of disorders of the physiological and reparative regeneration of tissues of the musculoskeletal system, including patients with diabetes mellitus.Изобретение относится к области медицины и фармации, а именно к созданию фармацевтической композиции в виде суспензии для профилактики и лечения нарушений физиологической и репаративной регенерации тканей опорно-двигательной системы - костной ткани и суставного хряща, в частности для лечения остеопороза. Фармацевтическая композиция для профилактики и лечения нарушений физиологической и репаративной регенерации