THE TRUSTEES OF PRINCETON UNIVERSITY;ELI LILLY AND COMPANY
发明人:
TAYLOR, EDWARD C.,KUHNT, DIETMAR G.,SHIH, CHUAN,GRINDEY, GERALD B.
申请号：
ES90123671
公开号：
ES2084639T4
申请日:
1990.12.10
申请国别(地区):
ES
年份:
2013
代理人:
摘要：
THE NUT (ACIL) GLUTAMIC ACID DERIVATIVES IN WHICH THE ACID GROUP IS REPLACED WITH A 4-HYDROXIPIRROLO GROUP [2, 3-D] -PIRIMIDIN-3-IL ARE ANTHINEOPLASTIC AGENTS. A TYPICAL PERSONIFICATION IS ACID N- [4- (2- {4-HIDROXI-6-AMINOPIRROLO [2, 3-D] PYRIMIDIN-3-IL} -ETIL) BENZOYL] -L-GLUTAMIC.LOS DERIVADOS DE ACIDO N-(ACIL)GLUTAMICO EN LOS QUE EL GRUPO ACIDO SE SUSTITUYE CON UN GRUPO 4-HIDROXIPIRROLO[2, 3-D]-PIRIMIDIN-3-IL SON AGENTES ANTINEOPLASTICOS. UNA TIPICA PERSONIFICACION ES ACIDO N-[ 4-(2-{ 4-HIDROXI-6-AMINOPIRROLO[ 2, 3-D]PIRIMIDIN-3-IL}-ETIL) BENZOILO]-L-GLUTAMICO.
