KUMAR, SHANKAR,TSURUSHITA, NAOYA,AHLIJANIAN, MICHAEL,JEFSON, MARTIN
申请号:
CA3082365
公开号:
CA3082365A1
申请日:
2018.11.08
申请国别(地区):
CA
年份:
2019
代理人:
摘要:
The present disclosure relates generally to conformation-specific antibodies that can bind to and neutralize the activity of phosphorylated-Threonine 231-tau protein (pT231-tau). The antibodies of the present technology are useful in methods for treating a neurological disorder associated with elevated cis-pT231-tau protein expression in a subject in need thereof.