Memorial Sloan Kettering Cancer Center;Massachusetts Institute of Technology
发明人:
Cheal, Sarah M.,Xu, Hong,Larson, Steven M.,Cheung, Nai-Kong,Wittrup, Karl Dane
申请号：
AU2016219534
公开号：
AU2016219534A1
申请日:
2016.02.09
申请国别(地区):
AU
年份:
2017
代理人:
摘要：
Described herein are multi-specific binding agents that bind A33 and 1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetic acid. Also provided herein are methods of using multi-specific binding agents or compositions thereof for the detection, prevention, and/or therapeutic treatment of diseases characterized by expression of the A33 glycoprotein antigen, in particular, colorectal cancer.
