The present invention provides a system for immobilization of a patient body part for radiotherapy applications comprising: a device comprising at least one flanged support member which is suitable to be mounted to a fixation surface and is adapted to receive and retain at least two sheets; a first sheet for covering the anatomical contours of a first area of said body part, and a second sheet for covering the anatomical contours of a second area of said body part which is not covered by the first sheet; whereby the system is adapted for supporting the immobilized body part free from the fixation surface by the two sheets and the device.