CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE;INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE (INRA)
发明人:
Pierre FAFOURNOUX
申请号：
US16727647
公开号：
US20200188533A1
申请日:
2019.12.26
申请国别(地区):
US
年份:
2020
代理人:
摘要：
A nucleic acid for the controlled expression of a nucleic acid encoding a pro-apoptotic protein in an individual, including: a regulatory polynucleotide including a minimal promoter and at least one AARE (amino acid response element) nucleic acid, the regulatory polynucleotide being activated in an individual upon consumption of a diet deficient in at least one essential amino acid； and a nucleic acid encoding a pro-apoptotic protein, which is placed under the control of the regulatory polynucleotide.
