PASLOSKE KIRBY SHAWN,LAU KAI,RICHARDSON SARAH JANE,WILLIS AMANDA AILEEN
申请号：
NZ70610112
公开号：
NZ706101A
申请日:
2012.11.27
申请国别(地区):
NZ
年份:
2016
代理人:
摘要：
Disclosed herein are injectable compositions comprising a cyclodextrin hydrophobic drug complex, water, a preservative selected from the group consisting of: m-cresol, chlorobutanol, boric acid, cetylpyridinium chloride, cetrimide, phenol, phenylethanol, phenoxyethanol, and mixtures thereof, a co-solvent selected from the group consisting of: ethanol, glycerin, propylene glycol, isopropyl alcohol, glycerol formal, tetraglycol, and mixtures thereof and optionally a buffer to provide a pH from about 4.0 to about 9.0. Also disclosed are methods of preserving injectable compositions by adding preservatives and a co-solvent and the use of these compositions in the manufacture of medicaments.
