Viking Therapeutics, Inc.;Metabasis Therapeutics, Inc.
发明人:
Brian Lian,Hiroko Masamune,Mark Erion,Bruce Ito
申请号:
US16333513
公开号:
US20190255080A1
申请日:
2017.09.13
申请国别(地区):
US
年份:
2019
代理人:
摘要:
The present disclosure is directed to methods of administration of thyroid hormone receptor agonists. The disclosure provides methods wherein the activity of the given thyroid receptor agonists in ameliorating or curing obesity, hyperlipidemia, hypercholesterolemia, diabetes, non-alcoholic fatty liver disease, non-alcoholic steatohepatitis, atherosclerosis, cardiovascular disease, hypothyroidism, and related disorders is maintained, while thyroid-related and thyroid axis-related side effects are reduced or eliminated.