Jonathan Joseph Powell,Nuno Jorge Rodrigues Faria,Carlos Andre Passos Bastos
申请号:
US16480363
公开号:
US20190380996A1
申请日:
2018.02.06
申请国别(地区):
US
年份:
2019
代理人:
摘要:
Copper based antibacterial agents are described based on amphiphilic copper complexes formed between copper and hydroxypyrones, such as maltol. In further aspects, the present invention relates to PEG based-ointments showing that they are particularly effective for topical delivery of amphiphilic complexes of copper. In particular, PEG ointments were shown to limit bacterial growth, even when in the absence of copper agent. However, this bacteriostatic effect is shown herein to become a true biocidal effect when copper hydroxypyrones are added to the PEG.