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PERCUTANEOUSLY ABSORBABLE PREPARATION CONTAINING FENTANYL AND HOMOLOGUE THEREOF
专利权人:
TRANSDERM INC.;SAMYANG BIOPHARMACEUTICALS CORPORATION
发明人:
Hyun-Suk Yu,Young-Moo Lee,Hyun-Woo Kim,Hee-Sook Kim
申请号:
US14346031
公开号:
US20140243765A1
申请日:
2012.09.21
申请国别(地区):
US
年份:
2014
代理人:
摘要:
Disclosed is a transdermal preparation, comprising sequentially-stacked layers of a backing layer, a barrier layer, a drug adhesive layer and a release layer, wherein the drug adhesive layer contains a drug selected from the group consisting of fentanyl, an analogue thereof and a pharmaceutically-acceptable salt thereof, a skin permeation enhancer of the drug, and a polyacrylate adhesive, which shows a high skin permeation with a low drug dosage, equivalent to one with high drug dosage, by increasing the skin permeation rate of drug.
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