A positioning device for use with a hypodermic needle. The positioning device 10 comprises a connector 42 for connecting to a hypodermic needle 40, a sheath 18 comprising a central region configured to accommodate a shaft of a hypodermic needle along its longitudinal axis and a convex or planar contact surface 20 for positioning on an injection site. A deformable link 16 may connect the sheath to the connector. The deformable link 16 may be a bow spring, compression spring or leaf spring. The contact surface 20 may be frusto-conical or part-spherical, and may be symmetrical about the longitudinal axis the surface 20 may be planar at an angle to the axis. Also claimed is a method of use wherein the contact surface is placed against the skin and pressing downwards upon the syringe to expose the needle.