Molecular control of brown fat differentiation and energy expenditure

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专利权人:

Patrick Seale

发明人:

Patrick Seale,Bruce M. Spiegelman

申请号：

US12446110

公开号：

US09074012B2

申请日:

2007.10.17

申请国别(地区):

US

年份:

2015

代理人:

摘要：

The invention provides methods and compositions for inducing brown fat cell differentiation through modulation of Prdm 16 activity or expression. Also provided are methods for preventing or treating obesity or an obesity related disorder in a subject through stimulation of Prdm 16 expression or activity. Further provided are methods for identifying compounds that are capable of modulating Prdm 16 expression or activity.

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