A method of manufacturing biodegradable materials for filling nasal cavity of the present invention comprises the following steps: a. within a predetermined temperature range, evenly mixing chitosan and the substrate (starch or cellulose) to make a first solution b. adding crosslinking agent in the first solution for crosslinking reaction c. pouring the first solution into the mold d. removing water through freeze-drying process, thereby the biodegradable materials for filling nasal cavity are obtained. The biodegradable materials are filled in patients nasal cavity to stop bleeding and avoid a second time injury by removing, because of biodegradable absorption.
