Scott D. Kuduk,Casey C. McComas,Thomas S. Reger,Changhe Qi
申请号:
US14769829
公开号:
US09353104B2
申请日:
2014.03.10
申请国别(地区):
US
年份:
2016
代理人:
摘要:
The present invention is directed to substituted pyridizinone compounds of formula I which are useful as therapeutic agents for the treatment of central nervous system disorders associated with phosphodiesterase 10 (PDE10). The present invention also relates to the use of such compounds for treating neurological and psychiatric disorders, such as schizophrenia, psychosis or Huntington's disease, and those associated with striatal hypofunction or basal ganglia dysfunction.