NAIRN, NATALIE WINBLADE,PRESNELL, SCOTT,JOCHHEIM, CLAUDIA,STROUD, MARK
申请号：
CA3093588
公开号：
CA3093588A1
申请日:
2019.03.15
申请国别(地区):
CA
年份:
2019
代理人:
摘要：
Truncated, variant, or mutated peptides that home, target, migrate to, are directed to, are retained by, or accumulate in and/or bind to the cartilage or kidney of a subject are disclosed. Pharmaceutical compositions and uses for truncated or mutated peptides or truncated or mutated peptide-active agent complexes comprising such peptides are also disclosed. Such compositions can be formulated for targeted delivery of an active agent to a target region, tissue, structure or cell in the cartilage. Targeted compositions of the disclosure can deliver truncated or mutated peptide or truncated, variant, or mutated peptides or peptide-active agent complexes to target regions, tissues, structures or cells targeted by the peptide.
