Icahn School of Medicine at Mount Sinai;Yeda Research and Development Co. Ltd. At the Weizmann Institute of Science
发明人:
SCHUCHMAN Edward H.,GULBINS Erich,FUTERMAN Anthony,PEWZNER-JUNG Yael
申请号：
SI201331715
公开号：
SI2854910T1
申请日:
2013.05.31
申请国别(地区):
SI
年份:
2020
代理人:
摘要：
The present invention relates to a method for treating or preventing pathogenic infections in a subject having Cystic Fibrosis, COPD, and/or an open wound. This method involves selecting a subject having Cystic Fibrosis, COPD, and/or an open wound and administering to the selected subject a ceramidase under conditions effective to reduce ceramide and to treat or prevent the pathogenic infection. Th e method also involves the use of a ceramidase in combination with other drugs to reduce infection, reduce ceramide, or improve lung function in Cystic Fibrosis, COPD, and/or open wound patients.
