N-arylmethyl sulfonamide negative modulators of NR2A

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专利权人:

发明人:

David R Anderson,Robert A Volkmann

申请号：

US15024870

公开号：

US09963434B2

申请日:

2014.09.26

申请国别(地区):

US

年份:

2018

代理人:

摘要：

Compounds of the Formulawherein A, B, C, D, X, Y, Z, R1, R2, R2′, R3 and n are described herein, selectively negatively modulate NMDA receptors containing an NR2A subunit, pharmaceutical compositions comprising the compounds, and methods of treating a disease using the compounds are disclosed.

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