Use of the association of a sinus node If current inhibitor and an angiotensin-converting enzyme inhibitor in the treatment of heart failure

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专利权人:

Les Laboratoires Servier

发明人:

Thuillez, Christian,Mulder, Paulus,Vilaine, Jean-Paul,Fratacci, Marie-Dominique,Lerebours-Pigeonniere, Guy,Feldmann, Luc,Roussel, Jerome

申请号：

AU2011202607

公开号：

AU2011202607A1

申请日:

2011.05.31

申请国别(地区):

AU

年份:

2012

代理人:

摘要：

#$%^&*AU2011202607A120120112.pdf#####USE OF THE ASSOCIATION OF A SINUS NODE IF CURRENT INHIBITOR AND AN ANGIOTENSIN-CONVERTING ENZYME INHIBITOR IN THE TREATMENT OF HEART FAILURE Abstract The invention relates to the use of the association of a selective and specific sinus node Ir current inhibitor, more especially ivabradine or N-{[(7S)-3,4dimethoxybicyclo[4.2.0]octa-1,3,5-trien-7-yl]methyl}-3-(7,8-dimethoxy-1,2,4,5tetrahydro-3H-3-benzazepin-3-yl)-N-methyl-3-oxo-1-propanamine, and an agent that 5 inhibits angiotensin-converting enzyme, in obtaining medicaments intended for the treatment of heart failure, more especially heart failure having preserved systolic function. Medicaments are also disclosed.

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