ANDERSON, CARTER R.,安德森 卡特R,安德森 卡特R,MORRIS, RUSSELL L.,莫里斯 罗素L,莫里斯 羅素L,EISCHEN, KATHLEEN A.,艾斯全 凯思琳A,艾斯全 凱思琳A
申请号：
TW098129405
公开号：
TWI454244B
申请日:
2009.09.01
申请国别(地区):
TW
年份:
2014
代理人:
摘要：
A wearable iontophoresis device for the prolonged delivery of a positively charged pharmaceutical species from a salt formulation is disclosed that includes a readily oxidizable metal-based sacrificial anode in the form of a generally planar layer having a connecting area that has a width that is sufficient to insure complete consumption of the oxidizable metal wherein the anode is configured to have a minimum operating life of at least 6 hours under skin-safe conditions, and a drug delivery gel pad in electrical contact with said anode for accommodating a gel containing a positively charged pharmaceutical species in salt form formulated for transdermal delivery.一種適用於延長電離子透入療法施用期的消耗性電極及其製造、使用方法與裝置,係關於一種可穿戴式電離子透入療法裝置,用來進行一陽極充電藥劑種類的延長傳送,其係來自鹽的配製,該裝置係包括一容易氧化金屬為基礎的犧牲性陽極,且通常係以平面層的形式,其係具有一寬度的連接區域可以充分確保該氧化金屬的完全耗盡,其中該陽極係被組設去具有一於皮膚安全的狀態下至少6小時的最小操作生命,與一藥物傳送凝膠墊係電性接觸於該陽極,其係可容納一凝膠,係包含一陽極充電藥劑種類且以鹽的形式被配製來進行穿越皮膚的傳送。30‧‧‧犧牲性電極32‧‧‧主電極34‧‧‧藥物墊的接觸區域36‧‧‧頸部區域(a-b)‧‧‧寬度(c-d)‧‧‧寬度
