Novel Compound, And Method For Producing Regulatory T Cells

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专利权人:

Kyoto University;Astellas Pharma Inc.

发明人:

Shimon SAKAGUCHI,Naganari OHKURA,Norihisa MIKAMI,Shuh NARUMIYA,Masahiko AKAMATSU,Guliang XIA,Hironori HARADA,Naoto NAKAMURA,Satoru UJIHARA,Hisao HAMAGUCHI

申请号：

US16479229

公开号：

US20190382403A1

申请日:

2018.01.30

申请国别(地区):

US

年份:

2019

代理人:

摘要：

Provided are a novel compound having CDK8 and/or CDK19 inhibitory activity, and a production method for Tregs. The treatment of T cells with a CDK8 and/or CDK19 inhibitor induces Foxp3 in the T cells. Foxp3+ T cells can be induced by treating Foxp3−； T cells with the CDK8 and/or CDK19 inhibitor in vitro. Thus, Tregs can be induced.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/