N-PYRIDINYL ACETAMIDE DERIVATIVES AS INHIBITORS OF THE WNT SIGNALING PATHWAY

• 收藏
• 分享

专利权人:

Redx Pharma PLC

发明人:

Inder Bhamra,Matilda Bingham,Richard Testar,Louise Sargent,Craig Donoghue

申请号：

US15514046

公开号：

US20170275276A1

申请日:

2015.10.08

申请国别(地区):

US

年份:

2017

代理人:

摘要：

Disclosed are compounds useful as inhibitors of the Wnt signalling pathway. Specifically, inhibitors of Porcupine (Porcn) are contemplated by the invention. In addition, the invention contemplates processes to prepare the compounds and uses of the compounds. The compounds of the invention may therefore be used in treating conditions mediated by the Wnt signalling pathway, for example, in treating cancer, sarcoma, melanoma, skin cancer, haematological tumors, lymphoma, carcinoma, and leukemia； or enhancing the effectiveness of an anti-cancer treatment.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/