Methods and systems for performing an interventional procedure are presented. A first set of pulses are delivered using at least one image sensor simultaneously with a second set of pulses delivered using at least one flow sensor disposed in an integrated interventional device towards a target region in a subject. Further, structural information corresponding to the target region at a designated time is determined using imaging signals received in response to the first sets of pulses. Additionally, volumetric information corresponding to the target region at the designated time is determined using signals received in response to the second sets of pulses. Moreover, the structural and volumetric information is processed using a determined model to compute one or more diagnostic parameters corresponding to the target region. A diagnostic assessment of the target region is then provided based on the computed diagnostic parameters.
