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17-hydroxy-19-nor-21-carboxylic acid-steroid γ-lactone derivative, use thereof, and medicament containing the derivative
专利权人:
Jan Hübner;Steffen Borden;Sven Ring;Katja Prelle;Rolf Bohlmann;Frederik Menges;Thomas Frenzel;Hans-Peter Muhn;Joachim Kuhnke;Ulrich Klar
发明人:
Ulrich Klar,Joachim Kuhnke,Rolf Bohlmann,Jan Hübner,Sven Ring,Thomas Frenzel,Frederik Menges,Steffen Borden,Hans-Peter Muhn,Katja Prelle
申请号:
US12810991
公开号:
US08937058B2
申请日:
2008.12.23
申请国别(地区):
US
年份:
2015
代理人:
摘要:
The invention relates to 17-hydroxy-19-nor-21-carboxylic acid-steroid γ-lactone derivatives with the chemical formula I, where R4, R6a, R6b, R7, R15, R16a, R16b, R18 and Z have the meanings stated in claim 1, and their solvates, hydrates, stereoisomers and salts. The invention further relates to the use of these derivatives for the production of a medicinal product for oral contraception and for the treatment of pre-, peri- and postmenopausal complaints and medicinal products that contain said derivatives. The derivatives according to the invention have a progestational and in preferred cases additionally an antimineralocorticoid and neutral to slightly androgenic action.
来源网站:
中国工程科技知识中心
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http://www.ckcest.cn/home/

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