GLICKLICH ALAN,KAM MARIA MATILDE SANCHEZ,SHANAHAN WILLIAM R
申请号：
IN201717027889
公开号：
IN201717027889A
申请日:
2017.08.04
申请国别(地区):
IN
年份:
2017
代理人:
摘要：
Provided are methods of treatment of a sphingosine 1 phosphate subtype 1 (S1P) receptor associated disorder comprising prescribing and/or administering to an individual in need thereof a standard dose of (R) 2 (7 (4 cyclopentyl 3 (trifluoromethyl)benzyloxy) 1 2 3 4 tetrahydrocyclopenta[]indol 3 yl)acetic acid (Compound 1) or a pharmaceutically acceptable salt hydrate or solvate thereof in an amount equivalent to about 1.5 to about 2.5 mg of Compound 1 for example a disease or disorder mediated by lymphocytes an autoimmune disease or disorder an inflammatory disease or disorder ankylosing spondylitis biliary cirrhosis cancer psoriasis psoriatic arthritis rheumatoid arthritis Crohn s disease transplant rejection multiple sclerosis systemic lupus erythematosus inflammatory bowel disease ulcerative colitis type I diabetes hypertensive nephropathy glomerulosclerosis myocardial ischemia reperfusion injury and acne.
