Skin normalizing agents containing at least one ingredient selected from thegroup consisting of ammonium salts and ion, compounds represented by generalformula (1) (wherein each symbol is as defined in the description), ionsthereof and pharmaceutically acceptable salts of the same. Examples of theactive ingredient include L-arginine and ethanolamine. These skin normalizingagents exert remarkable effects as agents for normalizing the skin barriermechanism and the skin function and preventives/remedies for atopic dermatitis.