The present invention relates to improved topical administration of one or more growth factors for non-surgical, cosmetic use. In particular, a combination of one or more growth factors with a microneedle roller. Specifically, the invention resides in a kit for cosmetic use comprising: one or more growth factors, growth factor mimetics, and/or growth factor receptor agonists formulated for topical application and means to perform wounding of skin, such as a microneedle array, wherein the wounding is targeted to at least the epidermis and/or dermis of the skin to release endogenous thrombin into dermal and/or epidermal tissue.
