Wolfgang WRASIDLO,Emily M. STOCKING,Adrian HALL,Malcolm MACCOSS
申请号:
US15748154
公开号:
US20180222899A1
申请日:
2016.07.29
申请国别(地区):
US
年份:
2018
代理人:
摘要:
The present invention relates to certain bis-heteroaryl compounds, pharmaceutical compositions containing them, and methods of using them, including methods for preventing, reversing, slowing, or inhibiting protein aggregation, and methods of treating diseases that are associated with protein aggregation, including neurodegenerative diseases such as Parkinsons disease, Alzheimers disease, Lewy body disease, Parkinsons disease with dementia, fronto-temporal dementia, Huntingtons Disease, amyotrophic lateral sclerosis, and multiple system atrophy, and cancer including melanoma.