ABSTRACT - 600243 The disclosure relates to an agent consisting of theobromine and a decongestant as a combined preparation for use in a therapy of cough, wherein the agent is manufactured for administration by an oral route, wherein the decongestant is selected from ephedrine, levmetamfetamine, naphazoline, oxymetazoline, phenylephrine, phenylpropanolamine, propylhexedrine, pseudoephedrine, synephrine and tetrahydrozoline, and wherein the decongestant, preferably pseudoephedrine, is to be administered in a dose of 0.1 to 30 mg/kg/day.