A method and device for image guided dynamic radiation treatment of prostate cancer and other pelvic lesions including: 1) a unique fan geometry of radiation sources 2) a special collimation method and apparatus to sculpt the radiation borders 3) an integrated three-dimensional imager and a special tissue interface imaging system to locate and track critical boundaries in real-time 4) a dynamic patient support system, which is shared by the said imager and the irradiation system and 5) motorized custom shielding filters to further protect neighboring normal tissues such as the kidneys and femoral heads. The fan geometry utilizes a plural number of radiation sources arranged specifically for irradiating tumors in the human pelvis while not harming critical structures, and the collimation sculpts the radiation borders using motorized shields for different sensitive structures. This allows high doses of radiation to be delivered to lesions within the human pelvis, such as the prostate, while sparing its surrounding structures, such as the rectum and bladder, as well as the urethra that is contained inside the prostate.