The Regents of the University of California;Vybyi Holdings, Inc.
发明人:
Clare L.M. Leguyader,Nathan Gianneschi,Cassandra E. Callmann,Matthew P. Thompson,Treffly Ditri,Paul A. Bertin
申请号:
US16492660
公开号:
US20200046859A1
申请日:
2018.04.25
申请国别(地区):
US
年份:
2020
代理人:
摘要:
The present disclosure generally provides compounds useful as MRI contrast agents. In some aspects, the disclosure provides MRI contrast agents that are chemically modified to have one or more moieties that include hydrophobic portions. In some aspects, the disclosure provides compositions that include such modified MRI contrast agents and a protein, such as albumin or albumin mimetics. Further, the disclosure provides various uses of these compounds and compositions.