Conformationally restricted PI3K and mTOR inhibitors

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专利权人:

Piqur Therapeutics AG;Universitaet Basel

发明人:

Cmiljanovic, Vladimir,Hebeisen, Paul,Jackson, Eileen,Beaufils, Florent,Bohnacker, Thomas,Wymann, Matthias

申请号：

AU2014331049

公开号：

AU2014331049A1

申请日:

2014.10.03

申请国别(地区):

AU

年份:

2016

代理人:

摘要：

The invention relates to novel phosphoinositide 3-kinase (PI3K) and mammalian target of rapamycin (mTOR) inhibitor compounds of formula (I) and (II), which are conformationally restricted, and for which the meaning of the substituents are listed in the description. Preferred compounds are those wherein X isoxygen, R

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