LEE, Kyung Eun,이경은,KANG, Seung Hyun,강승현,KIM, Youn Joon,김연준,NOH, Min Soo,노민수,LEE, Sang Kook,이상국
申请号：
KRKR2017/007948
公开号：
WO2018/021777A1
申请日:
2017.07.24
申请国别(地区):
WO
年份:
2018
代理人:
摘要：
The present invention relates to an external use skin preparation composition for alleviating skin inflammation, containing a natural extract mixture as an active ingredient. According to the present invention, an external use skin preparation composition, containing, as active ingredients, a mixture of holy basil, Mentha canadensis and Azadirachta indica extracts, inhibits the expression of inflammatory cytokines (IL-6, IL-8), which is caused by fine dust, thereby alleviating skin irritation and skin inflammation caused by fine dust, and thus the composition can be ultimately and effectively applied to a use such as acne prevention and alleviation, flushing alleviation, and dermatitis prevention and alleviation.Linvention porte sur une préparation pour la peau à usage externe pour soulager linflammation de la peau, contenant un mélange dextraits naturels en tant quingrédient actif. Selon la présente invention, la composition de la préparation cutanée à usage externe, contient, comme ingrédients actifs, un mélange de basilic holy, Mentha canadensis et Azadirachta indica extrait, inhibe lexpression de cytokines inflammatoires (IL-6, IL-8) provoquée par de fines poussières, ce qui permet datténuer lirritation et linflammation de la peau provoquée par la poussière fine. Ainsi la composition peut être appliquée efficacement pour la prévention et le soulagement de lacné, le soulagement des bouffées vasomotrices, et la prévention et le soulagement de la dermatite.본 발명은 천연 추출 혼합물을 유효성분으로 함유하는 피부염증 완화용 피부외용제 조성물에 관한 것이다. 본 발명에 따르면, 홀리바질, 박하, 님나무 추출 혼합물을 유효성분으로 함유하는 피부외용제 조성물은 미세먼지로 인한 염증 유도 사이토카인(IL-6, IL-8)의 발현을 억제하여 미세먼지에 의한 피부자극 및 피부염증완화를 나타냄으로써, 궁극적으로 피부 트러블 예방 및 개선, 홍조 개선, 피부염 예방 및 개선 등의 용도에 효과적으로 적용할 수 있다.
