GACHON UNIVERSITY OF INDUSTRY-ACADEMIC COOPERATION FOUNDATION;GIL MEDICAL CENTER
发明人:
Mee Sup Yoon,Jie Chen,Kook Son,Cheol Soo Choi,Sunghoon Kim,Jung Min Han
申请号：
US16678369
公开号：
US20200155655A1
申请日:
2019.11.08
申请国别(地区):
US
年份:
2020
代理人:
摘要：
The present invention relates to a composition comprising the UNE-L domain of leucyl-tRNA synthetase as an effective ingredient for increasing muscle. More particularly, the UNE-L domain of LRS according to the present invention, which is a region that controls activity of Vps34, activates mTORC1 involved in protein synthesis and increases myocyte differentiation and muscle fiber regeneration, thus finding useful application in muscle augmentation.
