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As inhibitors of EHMT1 and EHMT2, aminobenzene was used to replace Arilo or isoArilo compounds. (Divisional request 201802928).
专利权人:
EPIZYME; INC.
发明人:
CAMPBELL, John Emmerson,DUNCAN, Kenneth William,FOLEY, Megan Alene,HARVEY, Darren Martin,KUNTZ, Kevin Wayne,MILLS, James Edward John,MUNCHHOF, Michael John
申请号:
CL2019000815
公开号:
CL2019000815A1
申请日:
2019.03.28
申请国别(地区):
CL
年份:
2019
代理人:
摘要:
Described are Arilo compounds or heteromorphic compounds substituted with ammonia; pharmacological and amperometric compounds; EACUTE; props containing these compounds and M AMP; EACUTE; all disorder treatments (E.G.).Anemia Drepanoc Amp; IACUTE; TICA) by inhibition and amperometry; OACUTE; N selected from a methyltransferase, from EHMT1 to EHMT2, by managing this compound or this compound; OACUTE; N Pharma Amp; EACUTE; useful for people in need. TAMBI AMP; EACUTE; N describes the use of these compounds in the following studies: CI AMP; OACUTE; N or other non-therapeutic uses; EACUTE; uticos. LT; /P GT;<;p>;SE DESCRIBEN COMPUESTOS DE ARILO O HETEROARILO SUSTITUIDOS CON AMINO; COMPOSICIONES FARMACÉ;UTICAS QUE LOS CONTIENEN Y MÉ;TODOS DE TRATAMIENTO DE UN TRASTORNO (E.G., ANEMIA DREPANOCÍ;TICA) MEDIANTE LA INHIBICIÓ;N DE UNA ENZIMA METILTRANSFERASA SELECCIONADA ENTRE EHMT1 Y EHMT2, ADMINISTRANDO DICHO COMPUESTO O DICHA COMPOSICIÓ;N FARMACÉ;UTICA A UN SUJETO QUE LO NECESITE. TAMBIÉ;N SE DESCRIBE EL USO DE TALES COMPUESTOS EN INVESTIGACIÓ;N U OTROS FINES NO TERAPÉ;UTICOS.<;/p>;
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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