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N-((het)arylmethyl)-heteroaryl-carboxamides compounds as plasma kallikrein inhibitors
专利权人:
Kalvista Pharmaceuticals Limited
发明人:
Davie, Rebecca Louise,Edwards, Hannah Joy,Evans, David Michael,Hodgson, Simon Teanby
申请号:
AU2019240616
公开号:
AU2019240616A1
申请日:
2019.10.02
申请国别(地区):
AU
年份:
2019
代理人:
摘要:
#$%^&*AU2019240616A120191017.pdf#####C: Interwo n NRPortbl DCC SXD 19372483_I.docx-I/l0/2019 ABSTRACT The present invention provides compounds of formula (1): (1) compositions comprising such compounds; the use of such compounds in therapy (for example in the treatment or prevention of a disease or condition in which plasma kallikrein activity is implicated); and methods of treating patients with such compounds; wherein R5, R6, R7, A, B, W, X, Y and Z are as defined herein. A R6 ' H R7 N O B
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