CONTROLLED RELEASE CARVEDIOLOL FORMULATIONFIELD OF THE INVENTION5ABSTRACTA controlled release carvedilol formulation for less frequent, preferably once dailyadministration is described. The controlled release formulation comprises a therapeutically effective amount of carvedilol or a pharmaceutically acceptable salt thereof, a matrix forming polymer, a solubility enhancer and a pharmaceutically acceptable carrier. In one embodiment, a10controlled release formulation having a therapeutically effective amount of carvedilol iscontained in two or more subunits having different release profiles. The controlled release formulation is usable in the treatment and/or prophylaxis of one or more conditions such as cardiovascular disorders.15Fig. 8
