The Walter and Eliza Hall Institute of Medical Research
发明人:
Esther Bandala Sanchez,James Dromey,Leonard Charles Harrison,Yuxia Zhang,Maryam Rashidi
申请号:
US14351501
公开号:
US20140308209A1
申请日:
2012.11.15
申请国别(地区):
US
年份:
2014
代理人:
摘要:
The present disclosure relates to a soluble CD52 glycoprotein and its use in treating diseases regulated by effector T-cells, for example autoimmune diseases such as type 1 diabetes. The present disclosure also relates to fusion proteins comprising the soluble glycoprotein, to cells expressing high levels of CD52, and to diagnostic methods based on the detection of CD52 expression levels in a subject.